WebExpression of CDK5RAP2 (C48, CEP215, FLJ10867, MCPH3) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. WebSep 9, 2024 · Gene expression is reported as a z -score derived from RNA-seq data sets across n = 22 independent biological samples. f, Viability of patient-derived breast tumour organoids following a 14-d...
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WebFeb 11, 2024 · The expression of CDK5RAP2 is regulated by the Wnt signaling pathway. Depletion of CDK5RAP2 inhibits the tumorigenesis and migration of OSCC cells and alters the OSCC cancer stem (-like) cell (CSC) signature. Notably, suppression of CDK5RAP2 expression disrupts spindle orientation during mitosis. WebCDK5RAP2 (cyclin dependent kinase 5 regulatory subunit associated protein 2, also known as Cep215) is a centrosomal protein associated with a neurogenic disorder, the autosomal recessive primary microcephaly (Bond et al., 2005; From: International Review of Cell and Molecular Biology, 2010. View all Topics. Add to Mendeley. igor internet archive
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WebDec 20, 2024 · Conversely, inhibition of WIP1 activity increases p53 Ser15 phosphorylation and senescence in CDK5RAP2-depleted cells lacking GSK3β activity. These findings … WebFeb 17, 2011 · Cyclin-dependent kinase 5, regulatory subunit-associated protein 2 (CDK5RAP2), also referred to as centrosome-associated protein 215 (CEP215), CDK5 activator binding protein C48 (C48; a fragment), KIAA1633 and DKFZp686D1070, has moved into the spotlight because of its central function in human brain development and … WebExpression of CDK5RAP2 (C48, CEP215, FLJ10867, MCPH3) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We … is the cleaning lady renewed for 2023