Top6bl
Web11. máj 2016 · Function. Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the … Web19. júl 2024 · Study question: Are any novel mutations and corresponding new phenotypes, other than recurrent hydatidiform moles, seen in patients with MEI1 mutations? Summary …
Top6bl
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Web30. dec 2024 · An autosomal recessive mutation in TOP6BL was found co-segregating with infertility in this family. Investigation of one male patient revealed failure in programmed meiotic DSB formation and meiotic arrest prior to pachytene stage of prophase I. Mouse models carrying similar mutations to that in patients recapitulated the spermatogenic ... Web15. máj 2024 · Meiotic recombination is initiated by programmed DNA double-strand breaks at the beginning of meiotic prophase. C11ORF80, or TOPOVIBL, is the regulatory subunit …
Web22. mar 2024 · Recent studies showed that the expressions of DSB formation-related genes (Prdm9, Spo11, Top6bl, Hormad1, Mei1, and Mei4) are induced by the meiosis initiators STRA8 and MEIOSIN, which are activated by the binding of retinoic acid (RA) to its nuclear receptors (RXR/RAR heterodimers) (Ishiguro et al., 2024; Kojima et al., 2024; Raverdeau et … http://www.cogonline.com/info/132628664989445084
WebDownload scientific diagram A homozygous TOP6BL mutation identified from infertile Pakistani patients born to a consanguineous marriage. (a) The pedigree of the family. Squares represent males ... Web2 M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination. 来源：EMBO REP( P 1469-221X E 1469-3178 ) 发表时间: 2024/02. 类型：期刊论文 为本人加分
Web11. máj 2016 · Isoform 3. Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the …
Web26. feb 2016 · To investigate whether Top6bl has a role in meiotic DSB formation in mice, we generated point mutations in exon 9 of the Top6bl gene by means of CRISPR-Cas9 DSB … custom cabinet quoting open sourceWeb14. apr 2024 · 春深四月，嫩绿重重，好雨时节正发生。4月9日至11日，由四川省预防医学会、四川大学华西第二医院共同主办，四川省预防医学会妇科肿瘤预防与控制分会承办的“全国第九届妇科恶性肿瘤化学治疗及多学科综合治疗进展大会暨华西第二医院-华大基因学院第三届妇科遗传性肿瘤咨询师培训会暨四川 ... custom cabinet panama city flWeb7. feb 2024 · Top6bl null mice spermatocyte chromosome preparations and immunofluorescence were performed as previously described (Peters et al., 1997, Yang et … custom cabinet remodeling grove okWebNX_Q8N6T0 - TOP6BL - Type 2 DNA topoisomerase 6 subunit B-like - Portals. Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive … custom cabinet refinishing and repairWeb21. mar 2024 · Browse Primary Antibodies and Browse Secondary Antibodies. Boster Bio Custom Antibody Services (starting from $600), Antibody Validation Service, WB Service, … chassis straightening cairnschassis style industrielWeb29. mar 2024 · chromosome 11 open reading frame 80. Gene ID: 79703, updated on 26-Oct-2024. Gene type: protein coding. Also known as: HYDM4; TOP6BL; TOPOVIBL. See all available tests in GTR for this gene. Go to complete Gene record for C11orf80. Go to Variation Viewer for C11orf80 variants. custom cabinet pull outs